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Blastocyst transfer

Transferring blastocysts

Blastocyst transfer means transferral of embryos at a time when one or more of these is more mature during the development or blastocyst stage. Normally the embryo is at this stage on the fifth day after egg retrieval.

When the doctor has retrieved the eggs from an ovary, they are fertilised in the laboratory. This takes place via normal in vitro fertilisation (IVF) or intracytoplasmic-sperm injection (ICSI).

 

Immediately after fertilisation, the egg starts to divide and develops into an embryo. Blastocyst stages:

Day 1: the pronuclear stage (fertilised egg: pronuclear or PN stage),

Day 2: the 2–4-cell stage,

Day 3: the 8-cell stage,

Day 4: the mulberry or morula stage and

Day 5: blastocyst.

Normally, the doctor transfers one or more embryos into the woman’s womb two to three days after retrieving the eggs. This process is called embryo transfer.

Thanks to our improved cell culture media, today the embryos in the incubator can also be developed up until the fifth day, i.e. the blastocyst stage (blastocyst culture). If the doctor transfers these more developed embryos into the woman’s womb, we call this blastocyst transfer.

This method is being used more and more. If there are a lot of eggs to choose from between days 2 and 3, it may be best to wait, as it has been found that the best eggs on days 2 and 3 are not always the best blastocysts.

It may also be done if the doctor wants to know if the eggs have the potential to develop to this stage.

What are the advantages of blastocyst transfer?

The option of identifying embryos with development potential 

Only 20–30% of the fertilised eggs develop into blastocysts. When an embryo reaches this stage, there is a greater chance that it will implant in the womb.

The time is ideal during blastocyst transfer 

As with blastocyst transfer, an embryo from a naturally-conceived pregnancy reaches the womb on about the fifth day after fertilisation, where it implants. It is thought that the lining of the womb (the endometrium) is particularly receptive to the embryo on that day.

How likely is a successful result with blastocyst transfer?

There is a very high pregnancy rate with blastocyst transfer. Compared to the transfer of a fertilised eggs in the early blastocyst stage (days 2 or 3), the likelihood of a successful result is increased by about 7% (source DIR [das Deutsche IVF-Register - The German IVF Register] yearbook 2014). Women up to the age of 30 have a 45–50% chance per transfer of becoming pregnant, while the figures for women between 30 and 39 is about 35–40%. But blastocyst culture is not beneficial for all women. Our fertility doctors will discuss with you the transfer method that is best for you (personal individual treatment), so that you are afforded the best options of achieving a success.

Further topics you might be interested in

We are here for you!

Please feel free to contact us!

Our opening times:

Mon and Thu: 08:00 - 18:00
Tue, Wed and Fri: 08:00 - 16:00
Sat, Sun and holiday: 08:30 - 15:00

Schedule an appointment:

Fill out the contact form

✉ info[at]storkklinik.dk
+45 32 57 33 16

We look forward to hearing from you!